Customization: | Available |
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Grade: | Food Additive |
Resource: | Natural |
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What is Ciprofloxacin Hydrochloride?
Items | Specifications |
CHARACTERS | |
Appearance | Faintly yellowish to light yellow crystals. |
IDENTIFICATION | |
A.IR | IR spectrum of sample conforms to that of reference standard. |
B.HPLC | The retention time of the major peak of the sample solution corresponds to that of the standard solution,as obtained in the assay. |
C.Reaction of chlorides | A solution of it responds to the tests for Chloride |
ASSAY (on anhydrous basis) | 98.0%~102.0% of C17H18FN3O3·HCL |
Impurities | |
Inorganic Impurities | |
Residue on ignition | Not more than 0.1% |
Organic Impurities | |
Fluoroquinolonic acid (263nm) | Not more than 0.2% |
Any other Individual impurity (278nm) | Not more than 0.2% |
Total impurities (278nm) | Not more than 0.5% |
PH | 3.0~4.5 |
Water | 4.7%~6.7% |
Residual solvents | |
Ethanol | Not more than 4000ppm |
Bacterial endotoxin | Less than 0.20EU/mg |
Microbial limit | TAMC not more than 100cfu/g |
TAMC not more than 10cfu/g |
Ciprofloxacin is used to treat a wide variety of infections, including infections of bones and joints, endocarditis, gastroenteritis, malignant otitis externa, respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, and chancroid.
Ciprofloxacin only treats bacterial infections; it does not treat viral infections such as the common cold. For certain uses including acute sinusitis, lower respiratory tract infections and uncomplicated gonorrhea, ciprofloxacin is not considered a first-line agent.
Ciprofloxacin occupies an important role in treatment guidelines issued by major medical societies for the treatment of serious infections, especially those likely to be caused by Gram-negative bacteria, including Pseudomonas aeruginosa. For example, ciprofloxacin in combination with metronidazole is one of several first-line antibiotic regimens recommended by the Infectious Diseases Society of America for the treatment of community-acquired abdominal infections in adults.It also features prominently in treatment guidelines for acute pyelonephritis, complicated or hospital-acquired urinary tract infection, acute or chronic prostatitis,certain types of endocarditis, certain skin infections, and prosthetic joint infections.